MyBioSource.com's IBA57 Antibody - middle region is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Western Blot. The IBA57 Antibody - middle region was generated using IBA57, and iron-sulfur cluster assembly factor IBA57 as the antigen and it reacts with Human.
Description
The protein encoded by this gene localizes to the mitochondrion and is part of the iron-sulfur cluster assembly pathway. The encoded protein functions late in the biosynthesis of mitochondrial 4Fe-4S proteins. Defects in this gene have been associated with autosomal recessive spastic paraplegia-74 and with multiple mitochondrial dysfunctions syndrome-3. Two transcript variants encoding different isoforms have been found for this gene. The smaller isoform is not likely to be localized to the mitochondrion since it lacks the amino-terminal transit peptide